Proteolytic Cleavage of the ENaC gamma Subunit: Impact Upon Na+ and K+ Handling
Evan C. Ray, Andrew J. Nickerson, Shaohu Sheng, Rolando Carrisoza‐Gaytan, Tracey R. Lam, Allison L. Marciszyn, Lei Zhang, Alexa S. Jordahl, Chunming Bi, Aaliyah Winfrey, Zhaohui Kou, Sébastien Gingras, Annet Kirabo, Lisa M. Satlin, Thomas R. Kleyman
This study investigates the impact of proteolytic cleavage of the ENaC gamma subunit on Na+ and K+ handling in mice, finding that cleavage is not essential for channel activity in vivo.
American Journal of Physiology-Renal Physiology · Apr 18, 2024Peer-reviewedPhysiology