Sébastien Gingras

This study shows that ANT2 deficiency in AT2 cells promotes ferroptosis and emphysema by impairing bioenergetics and self-renewal.

A single amino acid substitution in CD28 enhances signaling, leading to increased CD8 activation and Tpex generation during viral infection, while accelerating exhaustion in chronic infection.

This study investigates the impact of proteolytic cleavage of the ENaC gamma subunit on Na+ and K+ handling in mice, finding that cleavage is not essential for channel activity in vivo.

This study generates a murine model of the human CREBRFR457Q obesity-risk variant and finds it does not affect energy or glucose homeostasis under various nutritional stress conditions.