Author

Aamir Mehmood

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Yinglong MiaoiD· 2 shared Adam FunkiD· 1 shared C.H. ArrowsmithiD· 1 shared David HaselbachiD· 1 shared Irina GrishkovskayaiD· 1 shared Jacqueline L. Norris-DrouiniD· 1 shared Jinan WangiD· 1 shared John R. Tabor· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Yinglong MiaoORCID

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2 papers

Recent·Most cited

Gaussian accelerated Molecular Dynamics - Thermodynamic Integration (GaMD-TI): Improved alchemical free energy calculations with enhanced sampling

Yinglong Miao, Skanda Sastry, Jinan Wang, Aamir Mehmood, Michael Tae-jong Kim

This paper introduces GaMD-TI, a method combining Gaussian accelerated MD with TI to improve free energy calculations by enhancing conformational sampling in alchemical transformations.

bioRxiv · Sep 3, 2026 · PreprintBiochemistry

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22

Kevin Robertson, Sascha Josef Amann, Tongkun Liu, Adam Funk, Xianxi Wang, Irina Grishkovskaya, Aamir Mehmood, John R. Tabor, Jacqueline L. Norris-Drouin, C.H. Arrowsmith, Jon L. Collins, Yinglong Miao, Michael J. Emanuele, David Haselbach, Lindsey Ingerman James, Nicholas Gene Brown

This paper reveals the structural basis of NSD2 degradation via SCF-FBXO22 recruitment, showing how aldehyde-based degraders induce conformational changes for covalent binding and efficient protein degradation.

Nature Communications · Apr 23, 2026Peer-reviewedBiochemistry