Author

Kevin Robertson

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aamir Mehmood· 1 shared Adam FunkiD· 1 shared Alexander Mazein· 1 shared C.H. ArrowsmithiD· 1 shared David HaselbachiD· 1 shared Guanghou Shui· 1 shared Holly Gibbs· 1 shared Irina GrishkovskayaiD· 1 shared

Activity by Year

2013-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Aamir Mehmood

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2 papers

Recent·Most cited

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22

Kevin Robertson, Sascha Josef Amann, Tongkun Liu, Adam Funk, Xianxi Wang, Irina Grishkovskaya, Aamir Mehmood, John R. Tabor, Jacqueline L. Norris-Drouin, C.H. Arrowsmith, Jon L. Collins, Yinglong Miao, Michael J. Emanuele, David Haselbach, Lindsey Ingerman James, Nicholas Gene Brown

This paper reveals the structural basis of NSD2 degradation via SCF-FBXO22 recruitment, showing how aldehyde-based degraders induce conformational changes for covalent binding and efficient protein degradation.

Nature Communications · Apr 23, 2026Peer-reviewedBiochemistry

A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

Steven Watterson, Maria-Luisa Guerriero, Mathieu Blanc, Alexander Mazein, Laurence Loewe, Kevin Robertson, Holly Gibbs, Guanghou Shui, Markus Wenk, Jane Hillston, Peter Ghazal

The paper models cholesterol biosynthesis pathway regulation, showing immune responses cause gradual flux reduction while statin-like treatments cause abrupt flux reduction, with immune regulation being more specific.

Biochimie · Mar 1, 2013Peer-reviewedSystems Biology