Author

Tongkun Liu

University of North Carolina at Chapel HillORCID 0000-0001-9653-0070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aamir Mehmood· 1 shared Adam FunkiD· 1 shared C.H. ArrowsmithiD· 1 shared David HaselbachiD· 1 shared Irina GrishkovskayaiD· 1 shared Jacqueline L. Norris-DrouiniD· 1 shared John R. Tabor· 1 shared Jon L. CollinsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aamir Mehmood

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedApr 23, 2026

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22

Kevin Robertson, Sascha Josef Amann, Tongkun Liu…·Nicholas Gene Brown

This paper reveals the structural basis of NSD2 degradation via SCF-FBXO22 recruitment, showing how aldehyde-based degraders induce conformational changes for covalent binding and efficient protein degradation.

2 citations

experimental assayprotein folding & dynamics

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