Author

John R. Tabor

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aamir Mehmood· 1 shared Adam FunkiD· 1 shared C.H. ArrowsmithiD· 1 shared David HaselbachiD· 1 shared Irina GrishkovskayaiD· 1 shared Jacqueline L. Norris-DrouiniD· 1 shared Jon L. CollinsiD· 1 shared Kevin Robertson· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aamir Mehmood

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1 paper

Recent·Most cited

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22

Kevin Robertson, Sascha Josef Amann, Tongkun Liu, Adam Funk, Xianxi Wang, Irina Grishkovskaya, Aamir Mehmood, John R. Tabor, Jacqueline L. Norris-Drouin, C.H. Arrowsmith, Jon L. Collins, Yinglong Miao, Michael J. Emanuele, David Haselbach, Lindsey Ingerman James, Nicholas Gene Brown

This paper reveals the structural basis of NSD2 degradation via SCF-FBXO22 recruitment, showing how aldehyde-based degraders induce conformational changes for covalent binding and efficient protein degradation.

Nature Communications · Apr 23, 2026Peer-reviewedBiochemistry