Galectin-3 Mediated Endocytosis of the Orphan G-Protein-Coupled Receptor GPRC5A
Abdeldjalil Boucheham, Jorge Mallor Franco, Séverine Bär, Ewan MacDonald, Solène Zuttion, Lana Blagec, Bruno Rinaldi, Johana Chicher, Lauriane Kühn, Philippe Hammann, Christian Wunder, Ludger Johannes, Hocine Rechreche, Sylvie Friant
This study identifies Galectin-3 as a novel ligand for GPRC5A, demonstrating its role in mediating endocytosis of the orphan GPCR in colorectal cancer cells.
Cells · Oct 9, 2025Peer-reviewedCell Biology