The human IG heavy chain constant gene locus is enriched for large structural variants and coding polymorphisms that vary among human populations
Uddalok Jana, Oscar L. Rodriguez, William Lees, Eric Engelbrecht, Zach Vanwinkle, Ayelet Peres, William S. Gibson, Kaitlyn M. Shields, Steven Schultze, Abdullah Dorgham, Matthew Emery, Gintaras Y. Deikus, Robert Sebra, Evan E. Eichler, Gur Yaari, , Corey T. Watson
The paper identifies structural variants and coding polymorphisms in the human IGHC locus, revealing population-specific diversity and potential functional impacts.
Cell Genomics · Oct 28, 2025Peer-reviewedGenomics