Author

Abigail Fowler

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Tuan Leng TayiD· 2 shared Aidan Conley KiefferiD· 1 shared Amritha Vinayak Manjally· 1 shared André FischeriD· 1 shared Andre Krunic· 1 shared Aoife Kateri O’ConnelliD· 1 shared Charles Lisboa· 1 shared Daisy Liljegren· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Tuan Leng TayORCID

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2 papers

Recent·Most cited

Spatiotemporal Characterization of Amyloidosis-Associated Microglial States Reveals Sex Difference in Early Plaque Formation

Amritha Vinayak Manjally, Abigail Fowler, Jiratchaya Thanayangyuen, Maximillian Cheval, Monica Iordanov, Daisy Liljegren, Yevah Milord, Jonathan Park, Ema Yamashita, Aidan Conley Kieffer, Tuan Leng Tay

This study examines sex differences in microglial responses to amyloid-beta plaques in 5XFAD mice, finding that female mice show increased plaque formation and microglial clustering at 4 months, while males have higher plaque load by 6 months.

bioRxiv · Aug 31, 2026 · PreprintNeuroscience

MicroRNA-223 Enhances Microglia-Dependent Clearance of Amyloid Beta Plaques and Ameliorates Behavioral Deficits in a Mouse Model of Alzheimer's Disease

Andre Krunic, Nikkitha Umesh Ganesh, Ugur Coskun, William Brennan, Patel Cd, Ojasi Joshi, Jane Lee, Tori Shiyang Gu, Jaclyn Caruso, Aoife Kateri O’Connell, Charles Lisboa, Nicholas A. Crossland, Margareta Kurkela, Julia TCW, Abigail Fowler, , Tiffany J. Mellott

This study shows that miR-223 improves cognitive function and reduces amyloid beta plaques in an Alzheimer's mouse model by enhancing microglial clearance.

bioRxiv · Jul 23, 2026 · PreprintNeuroscience