Temozolomide Induces Aberrant RNA Alkylation and Widespread Translational Repression
Jayden Rhodes, Abigail Grace Johnston, Katie Marlow, Xisheng Liu, John L. Hartman, Zhangli Su
This study shows temozolomide causes RNA alkylation and widespread translational repression in glioblastoma cells by targeting guanine-rich transcripts.
bioRxiv · Sep 3, 2026 · PreprintBiochemistry