Author

Jinwei Zhang

National Institute of Diabetes and Digestive and Kidney DiseasesORCID 0000-0002-2114-173XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jinwei Zhang1 paper · Johns Hopkins University

Biology Disciplines

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Molecular Biology· 2 Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Ilias SkeparniasiD· 2 shared Abigail Grace Johnston· 1 shared Alexandros ManiatisiD· 1 shared Anastassios VourekasiD· 1 shared Andrew H. KellumiD· 1 shared Andrew J. BrasingtoniD· 1 shared Ankur BothraiD· 1 shared Athanasios‐Nasir ShaukatiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMolecular Biology

Ilias SkeparniasORCID

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Author profile →

4 papers

Recent·Most cited

An ancestral tRNA maturation enzyme repurposed for cytoplasmic non-coding RNA processing

Athanasios‐Nasir Shaukat, Mahmoud F. Dondeti, Alexandros Maniatis, Ilias Skeparnias, Eleni G. Kaliatsi, Dimitrios G. Anastasakis, Jinwei Zhang, Anastassios Vourekas, Constantinos Stathopoulos

The paper identifies vtRNAs as direct substrates of ELAC1 and shows ELAC1 has broader RNA substrate specificity compared to ELAC2.

bioRxiv · Oct 9, 2026 · PreprintMolecular Biology

TRMT6/61A-mediated m1A methylation facilitates human pre-tRNA maturation and prevents surveillance by XRN2

Xisheng Liu, Nhi Yen Tran Nguyen, Abigail Grace Johnston, Ilias Skeparnias, Monima Anam, Katie Marlow, Naira Rehman, Andrew H. Kellum, Yinsheng Wang, Jinwei Zhang, Zhangli Su

This study shows TRMT6/61A-mediated m1A methylation on pre-tRNAs is essential for their maturation and prevents XRN2-mediated degradation, maintaining translational homeostasis.

bioRxiv · May 19, 2026 · PreprintGenetics

Specificity and mechanism of the double-stranded RNA-specific J2 monoclonal antibody

Charles Bou‐Nader, Kevin Maafu Juma, Ankur Bothra, Andrew J. Brasington, Rodolfo Ghirlando, Motoshi Suzuki, David N. Garboczi, Stephen Howard Leppla, Jinwei Zhang

This study defines the epitope, specificity, and mechanism of the J2 monoclonal antibody, revealing its unique recognition of dsRNA and implications for RNA research.

bioRxiv · May 9, 2025 · PreprintMolecular Biology

Systemic identification of functionally conserved lncRNA metabolic regulators in human and mouse livers

Chengfei Jiang, Zhe Li, Sunmi Seok, Ping Li, Yonghe Ma, Stephanie K. Podguski, Shria Moturi, Nao Yoneda, Kenji Kawai, Shotaro Uehara, Yasuyuki Ohnishi, Hiroshi Suemizu, Jinwei Zhang, Haiming Cao

The paper identifies functionally conserved lncRNA metabolic regulators in human and mouse livers that regulate triglyceride levels through a shared mechanism involving PABPC1 binding.

Gastroenterology · Aug 10, 2024Peer-reviewedPhysiology