Author

Xisheng Liu

University of Alabama at BirminghamORCID 0000-0002-8006-501XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Abigail Grace Johnston· 2 shared Katie MarlowiD· 2 shared Zhangli SuiD· 2 shared Andrew H. KellumiD· 1 shared Ilias SkeparniasiD· 1 shared Jayden Rhodes· 1 shared Jinwei ZhangiD· 1 shared John L. HartmaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

Abigail Grace Johnston

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 3, 2026

Temozolomide Induces Aberrant RNA Alkylation and Widespread Translational Repression

Jayden Rhodes, Abigail Grace Johnston, Katie Marlow…·Zhangli Su

This study shows temozolomide causes RNA alkylation and widespread translational repression in glioblastoma cells by targeting guanine-rich transcripts.

DOI 10.64898/2026.09.01.748722

humanbulk RNA-seq

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GeneticsbioRxivPreprintMay 19, 2026

TRMT6/61A-mediated m1A methylation facilitates human pre-tRNA maturation and prevents surveillance by XRN2

Xisheng Liu, Nhi Yen Tran Nguyen, Abigail Grace Johnston…·Zhangli Su

This study shows TRMT6/61A-mediated m1A methylation on pre-tRNAs is essential for their maturation and prevents XRN2-mediated degradation, maintaining translational homeostasis.

DOI 10.64898/2026.05.17.725798

humanexperimental assay

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