Chondrocyte-Specific Knockout of Piezo1 and Piezo2 Protects Against Post-Traumatic Osteoarthritis Structural Damage and Pain in Mice
Erica V. Ely, Kristin L. Lenz, Sophie G. Paradi, Seth Ack, Abraham Behrmann, Sarah Dunivan, Lauryn A. Braxton, Wolfgang Liedtke, Yong Chen, Kelsey H. Collins, Farshid Guilak
This study shows that knocking out Piezo1 and Piezo2 in chondrocytes protects against post-traumatic osteoarthritis structural damage and pain in mice.
Arthritis Research & Therapy · Jul 19, 2025Peer-reviewedPhysiology