Author

Adam H. Sachs

University of Denver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Daniel A. LinsemaniD· 1 shared Emily G. OldaniiD· 1 shared Erich G. ChapmaniD· 1 shared Kevin M Reynolds CaicedoiD· 1 shared McKenna E. Spaeth Herda· 1 shared Scott A. HorowitziD· 1 shared Sunil KumariD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Daniel A. LinsemanORCID

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1 paper

Recent·Most cited

The effect of G-quadruplexes on TDP43 condensation, distribution, and toxicity

Emily G. Oldani, Kevin M Reynolds Caicedo, McKenna E. Spaeth Herda, Adam H. Sachs, Erich G. Chapman, Sunil Kumar, Daniel A. Linseman, Scott A. Horowitz

This study shows that RNA G-quadruplexes influence TDP43 condensation and toxicity in different cell types, suggesting targeting these structures could be a new approach for treating protein misfolding diseases.

Structure · Aug 1, 2025Peer-reviewedMolecular Biology