Sunil Kumar

This study evaluates a cell-penetrating peptide (NCAM1-PrP) for its ability to inhibit IAPP aggregation and cytotoxicity in type II diabetes.

This study shows that RNA G-quadruplexes influence TDP43 condensation and toxicity in different cell types, suggesting targeting these structures could be a new approach for treating protein misfolding diseases.

This study investigates polyamine biosynthesis dysregulation in Alzheimer's disease and Down syndrome models, finding that DFMO reduces Aβ42 aggregation and AD-related protein levels in DS fibroblasts.

The paper combines regulatory element activity, gene expression, and genetic variation data across cell types to show how chromatin structure influences regulatory networks and genetic effects.