Cancer BiologybioRxivPreprint
Mesenchymal stromal cells release CXCL1/2/8 and induce chemoresistance and macrophage polarization
Bettina Couderc, Augustin Le Naour, Mélissa Prat…·Agnès Coste
This study identifies CXCL1/2/8 as factors released by cancer-associated mesenchymal stromal cells that induce chemoresistance and macrophage polarization, suggesting CXCR1/2 inhibition as a potential therapeutic strategy.
DOI 10.1101/482513