Human Stress Response Specificity through Biochemical Resonance Selectivity
Michael Worcester, Shayan Nejad, Arya Eimagh Naeini, Surya Arian, Devin O’Donnell, Pratyasha Mishra, Siyu Li, Kevin Yang, Aisa Anbir, Matthew G. Guevara, Nina Y. Yuan, Seán E. O’Leary, Marcus Kaul, Roya Zandi, Thomas E. Kuhlman
The paper demonstrates that human p38 MAPK selects targets through frequency-dependent biochemical resonance, using oscillating activation states to encode stimuli and activate specific genetic responses.
bioRxiv · Mar 5, 2025 · PreprintBiophysics