Seán E. O’Leary

This study maps SARS-CoV-2 protein-RNA interactions using eCLIP, revealing new regulatory sites for viral replication and translation.

This study uses single-molecule fluorescence assays to show that eIF4G represses eIF4E-cap binding, while eIF4A relieves this repression, revealing new insights into eIF4F dynamics and mRNA recognition.

The paper demonstrates that human p38 MAPK selects targets through frequency-dependent biochemical resonance, using oscillating activation states to encode stimuli and activate specific genetic responses.

This study identifies the RFTS domain of DNMT1 as a reader for H3K9me3/H3Ub, showing its role in DNA methylation maintenance and genomic stability.