Author

Matthew G. Guevara

University of California, Riverside

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Roya ZandiiD· 2 shared Seán E. O’LearyiD· 2 shared Aisa Anbir· 1 shared Alexandra N. Huang· 1 shared Arrmund Neal· 1 shared Arya Eimagh NaeiniiD· 1 shared Devin O’Donnell· 1 shared Duo XuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

Roya ZandiORCID

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2 papers

Recent·Most cited

Dynamics and Regulation of mRNA Cap Recognition by Human eIF4F

Hea Jin Hong, Matthew G. Guevara, Siyu Li, Yankang Liu, Alexandra N. Huang, Eric C. Lin, Arrmund Neal, Duo Xu, Rong Hai, Roya Zandi, Seán E. O’Leary

This study uses single-molecule fluorescence assays to show that eIF4G represses eIF4E-cap binding, while eIF4A relieves this repression, revealing new insights into eIF4F dynamics and mRNA recognition.

bioRxiv · Jun 26, 2025 · PreprintBiophysics

Human Stress Response Specificity through Biochemical Resonance Selectivity

Michael Worcester, Shayan Nejad, Arya Eimagh Naeini, Surya Arian, Devin O’Donnell, Pratyasha Mishra, Siyu Li, Kevin Yang, Aisa Anbir, Matthew G. Guevara, Nina Y. Yuan, Seán E. O’Leary, Marcus Kaul, Roya Zandi, Thomas E. Kuhlman

The paper demonstrates that human p38 MAPK selects targets through frequency-dependent biochemical resonance, using oscillating activation states to encode stimuli and activate specific genetic responses.

bioRxiv · Mar 5, 2025 · PreprintBiophysics