Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease.
Panjaporn Chaichana, Naphat Satapoomin, Chitrasak Kullapanich, Suthida Chuenklin, Aisha Mohammad, Manutsanun Inthawong, Erin E. Ball, Thomas Burke, Piyanate Sunyakumthorn, Jeanne Salje
This study compares seven strains of Orientia tsutsugamushi to identify virulence factors, finding no single gene or pattern predicts virulence, but highlighting complex interactions among effector proteins.
PLoS Pathogens · Jun 30, 2025Peer-reviewedMicrobiology