Panjaporn Chaichana

Comparative Dual RNA-Seq Analysis of Eight Orientia tsutsugamushi Strains in Endothelial Cells Reveals Regulatory Patterns in Bacterial and Host Pathways During Infection

The paper compares dual RNA-seq data from eight Orientia tsutsugamushi strains in endothelial cells, finding no clear gene expression patterns correlating with virulence but identifying strain-specific interferon responses and conserved bacterial pathways.

The intracellular bacterium Orientia tsutsugamushi hijacks the adaptor protein BICD2 for dynein-based motility

This study identifies how Orientia tsutsugamushi uses ScaC to recruit BICD2 for dynein-based motility, revealing a mechanism for bacterial transport within host cells.

Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease.

This study compares seven strains of Orientia tsutsugamushi to identify virulence factors, finding no single gene or pattern predicts virulence, but highlighting complex interactions among effector proteins.