LEMONmethyl-seq: Targeted long-read DNA methylation profiling reveals dynamics of CRISPR epigenome editing and endogenous DNA methylation patterns
Anna E. Christenson, Nikita S. Divekar, Justin P. Lubin, Luis G Palma, Peter J. Colias, Rithu K. Pattali, Da Zhuan Xu, Akane Hubbard, Katie Lin, Ngan Phan, Bernardo D Moreno, Sarah Chasins, S. John Liu, James K. Nuñez
LEMONmethyl-seq profiles DNA methylation dynamics in mammalian cells, revealing CRISPR-induced changes and endogenous patterns, including non-canonical CpH methylation.
bioRxiv · Feb 25, 2026 · PreprintMolecular Biology