Author

S. John Liu

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adam D LonghurstiD· 1 shared Akane Hubbard· 1 shared Anna E. ChristensoniD· 1 shared Beiduo RaoiD· 1 shared Bernardo D Moreno· 1 shared Da Zhuan XuiD· 1 shared Harish N. VasudevaniD· 1 shared Hiten D. MadhaniiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMolecular Biology

Adam D LonghurstORCID

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Author profile →

3 papers

Recent·Most cited

LEMONmethyl-seq: Targeted long-read DNA methylation profiling reveals dynamics of CRISPR epigenome editing and endogenous DNA methylation patterns

Anna E. Christenson, Nikita S. Divekar, Justin P. Lubin, Luis G Palma, Peter J. Colias, Rithu K. Pattali, Da Zhuan Xu, Akane Hubbard, Katie Lin, Ngan Phan, Bernardo D Moreno, Sarah Chasins, S. John Liu, James K. Nuñez

LEMONmethyl-seq profiles DNA methylation dynamics in mammalian cells, revealing CRISPR-induced changes and endogenous patterns, including non-canonical CpH methylation.

bioRxiv · Feb 25, 2026 · PreprintMolecular Biology

Interferon signaling underlies radiotherapy responses in malignant peripheral nerve sheath tumors (MPNSTs)

Iowis Zhu, Julian Chien, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steven E. Braunstein, Line G Jacques, Melike Pekmezci, S. John Liu, Harish N. Vasudevan

This study identifies interferon signaling as a key mediator of radiotherapy response in MPNSTs, linking it to T-cell recruitment and clinical outcomes.

International Journal of Radiation Oncology*Biology*Physics · Sep 1, 2025Peer-reviewedCancer Biology

A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast C. neoformans

Jordan E. Burke, Adam D Longhurst, Prashanthi Natarajan, Beiduo Rao, S. John Liu, Jade Sales-Lee, Yasaman Mortensen, James J. Moresco, Jolene K. Diedrich, John R. Yates, Hiten D. Madhani

The paper identifies five novel genes required for RNAi-mediated transposon suppression in C. neoformans, revealing a non-Dicer RNase III and nucleolar factors involved in endo-siRNA biogenesis.

G3 Genes Genomes Genetics · May 16, 2019Peer-reviewedMolecular Biology