Author
University of California, Berkeley
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Nikita S. Divekar, Ngan Phan, Luis G Palma, Justin P. Lubin, Anna E. Christenson, Scarleth C Ulloa, Peter J. Colias, Da Xu, Jamin Liu, Shaoni Mukhopadhyay, Bernardo D Moreno, Amy SY Lee, Sarah Chasins, James K. Nuñez
The paper shows RNA m6A modifications coordinate with de novo DNA methylation to establish heritable epigenetic silencing in human cells.
bioRxiv · Oct 22, 2026 · PreprintGenetics
Amanda McQuade, Reet Mishra, Venus Hagan, Weiwei Liang, Peter J. Colias, Vincent Cele Castillo, Bianca Gonzalez, Justin P. Lubin, Verena Claudia Haage, Victoria S. Marshe, Masashi Fujita, Thomas Ta, Layla Gomes, Olivia M. Teter, Xia Han, , Martin Kampmann
The paper identifies regulators of microglial activation states using CRISPR screens and single-cell transcriptomics, revealing functional roles of ZNF532, PRDM1, and DNMT1 in disease-associated microglial states.
Neuron · Jul 29, 2026Peer-reviewedNeuroscience
Jinna I. Brim, Izaiah J. Ornelas, Peter J. Colias, Nikita S. Divekar, Da Xu, Justin P. Lubin, Sophia I Ferrel, Luis G Palma, Mitzi G Hernández Zamora, Rithu K. Pattali, Jameel J McDaniel, Sarah Chasins, James K. Nuñez
CRISPRtune is a programmable tool that tunes transcriptional repression by fusing MeCP2 to dCas9, enabling intermediate gene expression control in human cells.
bioRxiv · Jul 10, 2026 · PreprintGenomics
Anna E. Christenson, Nikita S. Divekar, Justin P. Lubin, Luis G Palma, Peter J. Colias, Rithu K. Pattali, Da Zhuan Xu, Akane Hubbard, Katie Lin, Ngan Phan, Bernardo D Moreno, Sarah Chasins, S. John Liu, James K. Nuñez
LEMONmethyl-seq profiles DNA methylation dynamics in mammalian cells, revealing CRISPR-induced changes and endogenous patterns, including non-canonical CpH methylation.
bioRxiv · Feb 25, 2026 · PreprintMolecular Biology
Da Zhuan Xu, Swen Besselink, Gokul N. Ramadoss, Philip H. Dierks, Justin P. Lubin, Rithu K. Pattali, Jinna I. Brim, Anna E. Christenson, Peter J. Colias, Izaiah J. Ornelas, Carolyn D. Nguyen, Sarah Chasins, Bruce R. Conklin, James K. Nuñez
This paper introduces RENDER, a method for transient delivery of CRISPR-based epigenome editors as ribonucleoproteins to modulate gene expression in human cells, achieving durable epigenetic silencing.
Nature Communications · Aug 26, 2025Peer-reviewedGenetics