Active repression of muscle fate preserves neural lineage identity during cerebellum development
Shaikh Mirja Nurunnabi, Venkata Thulabandu, Akira Inoue, Joshua Paré, Jacqueline L. Norrie, Qiong Zhang, Beisi Xu, Xinwei Cao
The paper shows that active repression by the TEAD-INSM1 complex maintains neural identity during cerebellum development by preventing muscle fate activation.
bioRxiv · May 15, 2026 · PreprintDevelopmental Biology