Author

Sahil Seth

The University of Texas MD Anderson Cancer CenterORCID 0000-0003-4579-3959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Huandong Sun· 2 shared P. Andrew FutrealiD· 2 shared Samirkumar B. AminiD· 2 shared Xingzhi SongiD· 2 shared Xizeng Mao· 2 shared Akira Inoue· 1 shared Alexander Weiss· 1 shared Amy H.Y. TongiD· 1 shared

Activity by Year

2015-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Huandong Sun

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 22, 2025

Evolution of chronic lymphocytic leukemia after allogeneic stem cell transplant

Haven R. Garber, Danwei Wang, Céline Kerros…·Jeffrey J. Molldrem

This study examines how allogeneic stem cell transplant affects subclonal evolution in chronic lymphocytic leukemia, identifying cellular homogeneity as a biomarker for immune response.

DOI 10.1101/2025.01.22.634212

humanwhole-exome sequencing

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GenomicsbioRxivPreprintOct 14, 2018

Process-specific somatic mutation distributions vary with three-dimensional genome structure

Kadir Caner Akdemir, Victoria T. Le, Sarah Killcoyne…·P. Andrew Futreal

The paper examines how somatic mutation distributions vary across chromatin folding domains in cancer genomes, revealing distinct patterns associated with different mutational processes.

1 citation

humanwhole-genome sequencing

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Systems BiologybioRxivPreprintMar 16, 2017

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

Traver Hart, Amy H.Y. Tong, Katie Chan…·Jason Moffat

The paper evaluates CRISPR/Cas9 knockout screens in human cell lines and designs an optimized gRNA library to improve gene knockout efficiency and accuracy.

34 citations

humanCRISPR screen

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BioinformaticsbioRxivPreprintOct 22, 2015

Flowr: Robust and efficient pipelines using a simple language-agnostic approach

Sahil Seth, Samir Amin, Xingzhi Song…·Jianhua Zhang

Flowr provides a robust, scalable, and portable framework for designing computing pipelines using a simple language-agnostic approach.

DOI 10.1101/029710

experimental assaysoftware / tool

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