Concordant transcriptional and morphological remodeling revealed by in vivo Perturb-CLEAR
Boli Wu, Sean Simmons, Seoyeon Kim, Jiwen Li, Masood A. Akram, Chang Sin Park, Xinhe Zheng, Iain Mendez, Sasha Patel, Alan Chau, Nadia Burciu, Pranay Dayal, Thokozile Nyasulu, Nhan Huynh, Grace S. Clarke, , Xin Jin
The paper develops Perturb-CLEAR to study dendritic morphogenesis in the developing mouse cortex, revealing gene-specific multimodal phenotypes linked to NDD risk genes.
bioRxiv · Apr 8, 2026 · PreprintNeuroscience