Masood A. Akram

The paper develops Perturb-CLEAR to study dendritic morphogenesis in the developing mouse cortex, revealing gene-specific multimodal phenotypes linked to NDD risk genes.

Gossamer improves neuronal reconstruction by enabling whole-brain processing with reduced memory usage and higher automated yield compared to existing methods.

The paper introduces a pipeline to profile dendritic morphology of genetically-defined single neurons in the mouse brain, revealing morphological modules and age- or HD-associated changes.

The paper presents a similarity search tool for comparing neural morphologies across species and brain regions using morphometric and vectorized descriptors.

The paper uses genetic labeling and high-resolution microscopy to reveal fine-grained subtypes of cortical interneurons in mice, showing distinct connectivity patterns.