A selective GSK3β inhibitor, tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL/6J mice
Sam Gottlieb, Andrew D. van der Vaart, Annalise Hassan, Douglas Bledsoe, Alanna Morgan, Brennen O'Rourke, Walker D. Rogers, Jennifer T. Wolstenholme, Michael F. Miles
This study shows that tideglusib, a GSK3β inhibitor, reduces ethanol consumption in mice without affecting water intake or anxiety-like behavior.
Addiction Biology · May 1, 2025Peer-reviewedPharmacology & Toxicology