The C. elegans Notch proteins LIN-12 and GLP-1 are tuned to lower force thresholds for activation than Drosophila Notch
Paul D. Langridge, Alejandro Garcia Diaz, Jessica Yu Chan, Iva Greenwald, Gary Struhl
This study shows that C. elegans Notch proteins LIN-12 and GLP-1 have lower force thresholds for activation compared to Drosophila Notch, and a Leucine plug in vertebrate Notch proteins increases force requirements for activation.
Current Biology · Mar 28, 2022Peer-reviewedDevelopmental Biology