Author

Jessica Yu Chan

Columbia University

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Developmental Biology· 1

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Organism:C. elegans· 1 Approach:experimental assay· 1

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Alejandro Garcia Diaz· 1 shared Gary StruhliD· 1 shared Iva GreenwaldiD· 1 shared Paul D. LangridgeiD· 1 shared

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2022-2022 · peak 1/yr

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Alejandro Garcia Diaz

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Recent·Most cited

Developmental BiologyCurrent BiologyPeer-reviewedMar 28, 2022

The C. elegans Notch proteins LIN-12 and GLP-1 are tuned to lower force thresholds for activation than Drosophila Notch

Paul D. Langridge, Alejandro Garcia Diaz, Jessica Yu Chan…·Gary Struhl

This study shows that C. elegans Notch proteins LIN-12 and GLP-1 have lower force thresholds for activation compared to Drosophila Notch, and a Leucine plug in vertebrate Notch proteins increases force requirements for activation.

11 citations

C. elegansexperimental assay

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