Author

Iva Greenwald

Columbia UniversityORCID 0000-0001-7180-3706Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alejandro Garcia Diaz· 1 shared Gary StruhliD· 1 shared Jessica Yu Chan· 1 shared Justin M. Shaffer· 1 shared Paul D. LangridgeiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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1 shared paperDevelopmental Biology

Alejandro Garcia Diaz

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2 papers

Recent·Most cited

Developmental BiologyCurrent BiologyPeer-reviewedMar 28, 2022

The C. elegans Notch proteins LIN-12 and GLP-1 are tuned to lower force thresholds for activation than Drosophila Notch

Paul D. Langridge, Alejandro Garcia Diaz, Jessica Yu Chan…·Gary Struhl

This study shows that C. elegans Notch proteins LIN-12 and GLP-1 have lower force thresholds for activation compared to Drosophila Notch, and a Leucine plug in vertebrate Notch proteins increases force requirements for activation.

11 citations

C. elegansexperimental assay

𝕏 PostBluesky

GeneticsProceedings of the National Academy of SciencesPeer-reviewedJan 13, 2022

A Floxed exon (Flexon) approach to Cre-mediated conditional gene expression

Justin M. Shaffer, Iva Greenwald

The paper introduces Flexon, a stop cassette that enables Cre-mediated conditional gene expression by inserting into the coding region of any gene, allowing for precise control of gene expression in developmental studies.

17 citations

C. elegansexperimental assay

𝕏 PostBluesky