Author

Alejandro Hernandez Martinez

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexey V. SorokiniD· 1 shared Amanda AndersoniD· 1 shared Andrea VialeiD· 1 shared Annette A. MachadoiD· 1 shared Chi Wut WongiD· 1 shared Chris Bristow· 1 shared Christine Megerdichian ParseghianiD· 1 shared Dionne Prescod· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexey V. SorokinORCID

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1 paper

Recent·Most cited

Adaptive Plasticity Tumor Cells Modulate MAPK-Targeting Therapy Response in Colorectal Cancer

Oscar Eduardo. Villarreal, Yixin Xu, Ha Tran, Annette A. Machado, Dionne Prescod, Amanda Anderson, Rosalba Minelli, Mike Peoples, Alejandro Hernandez Martinez, Hey Min Lee, Chi Wut Wong, Natalie Wall Fowlkes, Preeti Kanikarla Marie, Alexey V. Sorokin, Jumanah Yousef Alshenaifi, , Scott Kopetz

The paper identifies adaptive plasticity tumor (APT) cells that reduce response to MAPK inhibitors in colorectal cancer by increasing stemness and ASCL2 expression, and shows that targeting APT cells improves therapy efficacy.

bioRxiv · Jan 22, 2025 · PreprintCancer Biology