Author

Aleksej Frolov

The University of MelbournePrimary ORCID profile (0000-0002-4406-1206 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Aleksej FroloviD2 papers · The University of Melbourne

Biology Disciplines

Click to filter author papers

Immunology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Lorenzo BonaguroiD· 3 shared Marc BeyeriD· 3 shared Anna NeubaueriD· 2 shared Axel KalliesiD· 2 shared Collins Osei-SarpongiD· 2 shared Darya MalkoiD· 2 shared Doaa HamadaiD· 2 shared Elena De DomenicoiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Lorenzo BonaguroORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Downregulation of Satb1 is required to prevent autoimmunity by maintaining Tfh homeostasis

Mehrnoush Hadaddzadeh Shakiba, Maren Köhne, Tarek Elmzzahi, Luisa Bach, Doaa Hamada, Leonie Heyden, Anna F. Lindemann, Jannis Bastian Spintge, Aleksej Frolov, Yuanfang Li, Lisa Holsten, Marlene Gottschalk, Celia Kho, Darya Malko, Collins Osei-Sarpong, , Marc Beyer

This study shows that Satb1 downregulation prevents autoimmunity by maintaining Tfh cell homeostasis and preventing excessive GC formation and auto-antibody secretion.

bioRxiv · Feb 5, 2026 · PreprintImmunology

Molecular determinants of brain-resident CD8+ T cell formation and function

Tarek Elmzzahi, Chun-Hsi Su, Mehrnoush Hadaddzadeh Shakiba, Doaa Hamada, Darya Malko, Maren Köhne, Aleksej Frolov, Teisha Mason, Rebekka Scholz, Yuanfang Li, Collins Osei-Sarpong, Leonie Heyden, Jonas Schulte-Schrepping, Lorenzo Bonaguro, Kristian Händler, , Marc Beyer

This study identifies molecular factors shaping brain-resident CD8+ T cell formation and function in health and disease.

bioRxiv · Aug 26, 2025 · PreprintImmunology

Unveiling the Power of High-Dimensional Cytometry Data with cyCONDOR

Charlotte Kröger, Sophie Merit Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat‐Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, DELCODE Study Group, Silka Dawn Freiesleben, Slawek Altenstein, Boris‐Stephan Rauchmann, Ingo Kilimann, , Lorenzo Bonaguro

The paper introduces cyCONDOR, a computational framework for high-dimensional cytometry data analysis, offering scalable and user-friendly tools for preprocessing, clustering, and downstream biological interpretation.

Nature Communications · Dec 19, 2024Peer-reviewedBioinformatics