Author

Alessandra Perfetto

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Roderik M. KortleveriD· 2 shared Stefan BoeingiD· 2 shared Tania CamposiD· 2 shared Abigail R. EdwardsiD· 1 shared CM Lam· 1 shared Gérard I. EvaniD· 1 shared GI EVAN· 1 shared Jonathan ParkeriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Roderik M. KortleverORCID

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2 papers

Recent·Most cited

Myc inhibition triggers GM-CSF-driven regression of pancreatic tumours

Tania Campos, Roderik M. Kortlever, Nicole M. Sodir, Michael D. Buck, Julie Stockis, Jonathan Parker, CM Lam, Juan Rodrigo Patiño-Mercau, Alessandra Perfetto, Abigail R. Edwards, Stefan Boeing, TYF Halim, GI EVAN

This study shows that inhibiting Myc in pancreatic tumours triggers GM-CSF release, which drives tumour regression via cDC1s, offering a new therapeutic strategy for PDAC.

bioRxiv · Feb 25, 2026 · PreprintCancer Biology

Targeting Myc activates a tissue-specific tumour resolution programme

Roderik M. Kortlever, Tania Campos, Stefan Boeing, Kazimir Uzwyshyn-Jones, Alessandra Perfetto, Gérard I. Evan

This study shows that targeting Myc in lung adenocarcinoma activates an immune programme that drives tumour regression through IL-33-mediated eosinophil recruitment.

bioRxiv · Feb 9, 2026 · PreprintCancer Biology