Author

Roderik M. Kortlever

King's College LondonORCID 0000-0001-5558-2851Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alessandra Perfetto· 2 shared Stefan BoeingiD· 2 shared Tania CamposiD· 2 shared Abigail R. EdwardsiD· 1 shared CM Lam· 1 shared Gérard I. EvaniD· 1 shared GI EVAN· 1 shared Jonathan ParkeriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Alessandra Perfetto

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 25, 2026

Myc inhibition triggers GM-CSF-driven regression of pancreatic tumours

Tania Campos, Roderik M. Kortlever, Nicole M. Sodir…·GI EVAN

This study shows that inhibiting Myc in pancreatic tumours triggers GM-CSF release, which drives tumour regression via cDC1s, offering a new therapeutic strategy for PDAC.

1 citation

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 9, 2026

Targeting Myc activates a tissue-specific tumour resolution programme

Roderik M. Kortlever, Tania Campos, Stefan Boeing…·Gérard I. Evan

This study shows that targeting Myc in lung adenocarcinoma activates an immune programme that drives tumour regression through IL-33-mediated eosinophil recruitment.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky