Author

Alex De Lecea

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Anthony StrockiD· 1 shared Ariyanna Haygood· 1 shared Atif Hassan· 1 shared Christina L. GreeneiD· 1 shared Daniel KessleriD· 1 shared Eric R SzelenyiiD· 1 shared Evan SchwartziD· 1 shared Garret D. StuberiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperNeuroscience

Anthony StrockORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Three-Dimensional Fluid-Structure Interaction Reveals Trade-offs Among Oxygen Delivery, Shear, and Washout in Pediatric Roller-Pump Cardiopulmonary Bypass

Yunpeng Tu, Yi‐Ting Yeh, Alex De Lecea, Kevin A. Charette, Lyubomyr Bohuta, Vishal Nigam, Juan C. del Álamo, Christina L. Greene

This study uses a 3D fluid-structure interaction model to show that pediatric roller-pump settings with similar oxygen delivery can result in different shear and washout environments, suggesting the need for joint evaluation of these metrics.

bioRxiv · Oct 28, 2026 · PreprintBioengineering

Hierarchical and Spatial Mapping of Whole-Brain c-Fos Activity Reveals Distinct Opioid and Withdrawal Neuronal Ensembles

Kentaro K. Ishii, Yizhe Y. Zhang, Lynn Y. Ren, Alex De Lecea, Suruchi Bakshi, Ariyanna Haygood, Sakura Chujo, Hannah P. Stevenson, Evan Schwartz, Zhe Charles Zhou, Eric R Szelenyi, Sam A. Golden, Daniel Kessler, Garret D. Stuber

The paper maps whole-brain c-Fos activity to identify distinct neuronal ensembles associated with morphine administration and withdrawal, revealing their spatial and molecular characteristics.

bioRxiv · Sep 21, 2025 · PreprintNeuroscience

Biophysical validation of explainable AI for functional brain imaging: bridging cellular mechanisms and network dynamics

Anthony Strock, Trang-Anh E. Nghiem, Alex De Lecea, Atif Hassan, Srikanth Ryali, Vinod Menon

This paper validates an explainable AI framework to identify brain regions affected by excitation/inhibition imbalance using simulations and empirical data from autism.

bioRxiv · Feb 24, 2025 · PreprintNeuroscience