Eric R Szelenyi

The paper maps whole-brain neural activity during emergence from isoflurane anesthesia in mice and finds selective subcortical activation rather than global cortical reactivation.

The paper maps whole-brain c-Fos activity to identify distinct neuronal ensembles associated with morphine administration and withdrawal, revealing their spatial and molecular characteristics.

This study identifies a brain-wide neural ensemble involved in anesthesia-induced unconsciousness, with the lateral parabrachial nucleus as a central hub.

The paper shows that male ejaculation reduces female sexual motivation by activating specific inhibitory neurons in the medial preoptic area of mice.

The paper identifies distinct functional roles of VTA dopamine subpopulations in reward association and motivation using electrophysiology and optogenetics in mice.

The paper introduces ArgiNLS, a nuclear localization signal that improves image segmentation of single-cells by restricting fluorescent proteins to the nucleus, enhancing machine learning-based segmentation.

The paper establishes a mouse model of incubation of palatable food craving and identifies brain-wide activation patterns using whole-brain activity mapping.

The paper quantifies whole-brain XCI at single-cell resolution and finds a 60:40 paternal-to-maternal inactivation ratio that reduces disease penetrance in Fragile-X models.

The paper develops genetic tools to dissect glutamatergic neuron subpopulations and their developmental trajectories in the cerebral cortex.

The paper develops enhancer viruses and a transgenic mouse line to enable combinatorial labeling of specific neuronal subclasses in the mouse cortex and human slices.