Kentaro K. Ishii

A cholinergic eligibility trace facilitates amygdala plasticity in flavour avoidance learning

This study shows that cholinergic input from the parabrachial nucleus to the central amygdala supports conditioned flavour avoidance learning by enabling long-timescale plasticity.

Subcortical recruitment dissociates isoflurane emergence from distinct wakeful states in mice

The paper maps whole-brain neural activity during emergence from isoflurane anesthesia in mice and finds selective subcortical activation rather than global cortical reactivation.

Hierarchical and Spatial Mapping of Whole-Brain c-Fos Activity Reveals Distinct Opioid and Withdrawal Neuronal Ensembles

The paper maps whole-brain c-Fos activity to identify distinct neuronal ensembles associated with morphine administration and withdrawal, revealing their spatial and molecular characteristics.

Anesthesia unconsciousness recruits dynamic parabrachial activity within a distributed brain-wide ensemble

This study identifies a brain-wide neural ensemble involved in anesthesia-induced unconsciousness, with the lateral parabrachial nucleus as a central hub.

Post-ejaculatory Inhibition of Female Sexual Drive via Heterogeneous Neuronal Ensembles in the Medial Preoptic Area

The paper shows that male ejaculation reduces female sexual motivation by activating specific inhibitory neurons in the medial preoptic area of mice.

Esr1-Dependent Signaling and Transcriptional Maturation in the Medial Preoptic Area of the Hypothalamus Shapes the Development of Mating Behavior during Adolescence

Single cell RNA sequencing reveals how adolescent sex hormones sculpt hypothalamic cell types required for mating behavior.

Opioid-driven disruption of the septal complex reveals a role for neurotensin- expressing neurons in withdrawal

The paper identifies Neurotensin-expressing neurons in the lateral septum as critical for opioid withdrawal by showing their activation and role in regulating withdrawal behaviors.