Cancer BiologybioRxivPreprint
Loss of CDKN2A remodels Golgi morphology to create a lipid peroxidation vulnerability
Amandine Amalric, Baixue Yang, Rebecca Scarpati…·Raquel Buj
The paper identifies altered Golgi morphology as a vulnerability in CDKN2A/p16-Low melanoma and shows that Golgi disruption via lipid peroxidation sensitizes these cells to treatment.