Author

Alexander Adrian-Hamazaki

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

Paul PavlidisiD· 2 shared Alexander M. MoriniD· 1 shared Aman SharmaiD· 1 shared Amelia RichteriD· 1 shared Andy Mungall· 1 shared Armaghan SarvariD· 1 shared BaRun Kim· 1 shared Beixi WangiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Paul PavlidisORCID

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Author profile →

3 papers

Recent·Most cited

Chromosomal mutational signatures of DNA damaging agents at single cell resolution

Mirela Andronescu, Alexander Adrian-Hamazaki, Damian Yap, William Daniels, Armaghan Sarvar, Elena Zaikova, Benjamin Furman, Vinci Au, Amelia Richter, Michael Van Vliet, Caroline Baril, Beixi Wang, Sean Beatty, Farhia Kabeer, Ciara H. O’Flanagan, , Samuel A. J. R. Aparicio

This paper develops a framework to analyze chromosomal mutational patterns at single-cell resolution, revealing drug-induced mutational signatures in human tissues.

bioRxiv · Sep 7, 2026 · PreprintCancer Biology

Gene function prediction from bulk coexpression is bounded by cell-type-level signal

Alexander Adrian-Hamazaki, Paul Pavlidis

This paper shows that gene function prediction from bulk coexpression is limited by cell-type-level resolution rather than fine-grained biochemical function.

bioRxiv · Sep 4, 2026 · PreprintBioinformatics

Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets

Alexander M. Morin, Eric Ching-Pan Chu, Aman Sharma, Alexander Adrian-Hamazaki, Paul Pavlidis

The paper integrates ChIP-seq and TR perturbation data to rank human and mouse TR-target interactions and identify orthologous relationships.

Genome Research · May 1, 2023Peer-reviewedBioinformatics