Author
BC Cancer AgencyORCID 0000-0002-2226-5988Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Jenkin Tsui, Naila Adam, Woongcheol Choi…·Nicholas A. Walton
Serval is a modular framework for decoding spatial transcriptomics data that introduces Cosine, a method improving transcript recovery and correlation with expression references.
Mirela Andronescu, Alexander Adrian-Hamazaki, Damian Yap…·Samuel A. J. R. Aparicio
This paper develops a framework to analyze chromosomal mutational patterns at single-cell resolution, revealing drug-induced mutational signatures in human tissues.
Farhia Kabeer, Matteo Lepur, Branden J. Lynch…·Andrew J. L. Roth
cfClone, a Bayesian model, deconvolves cfDNA whole-genome sequencing using scWGS-derived haplotype-specific clone copy-number profiles to estimate tumour fraction, clonal prevalence, and flag missed clones.
Marc J. Williams, Michael U. J. Oliphant, Vinci Au…·Samuel A. J. R. Aparicio
The paper analyzes copy number alterations in breast epithelial cells from BRCA mutation carriers and wildtype individuals, finding lineage-specific CNAs that mirror cancer genomes.
Helene Knævelsrud, Caroline Baril, Gwenaëlle Gavory…·Marc Therrien
This study identifies a RalGPS-Rala-exocyst-Rab11 pathway that regulates Pvr trafficking and signaling in Drosophila lymph glands, maintaining hematopoietic homeostasis.