Armaghan Sarvar

G4SCOPE predicts chromatin G-quadruplex occupancy from DNA sequence, revealing epigenetic differences in BRCA1 and BRCA2 deficient cells.

This paper develops a framework to analyze chromosomal mutational patterns at single-cell resolution, revealing drug-induced mutational signatures in human tissues.

The paper introduces Stash, a hash-based data structure for detecting genome misassemblies using Pacbio HiFi reads, showing it reduces misassemblies in human genome assemblies.

The paper investigates the mutational signature of CX5461, a photosensitiser, when combined with UVA light, showing increased SNV burden only in co-exposed cells.