Brush border intermicrovillar adhesion limits bacterial attachment to the small intestine brush border
Rebecca P. Cowell, Alexander C Bickart, Suchetha R Shashi, Ana Vásquez, Lee C. Brackman, Marwa A. Abdel-Dayem, Wei Chen, Deanna M Bowman, Evan Krystofiak, Yassine Essalki, Isabelle Groß, David Glenn Harrison, Celestine N. Wanjalla, Holly M. Scott Algood, Matthew J. Tyska, Leslie M. Meenderink
The paper shows that intermicrovillar adhesion complexes limit bacterial attachment to the small intestine brush border, with SFB remodeling actin to anchor to epithelial junctions.
bioRxiv · Nov 25, 2025 · PreprintCell Biology