Leslie M. Meenderink

The paper creates a spatial atlas of early-stage colorectal cancer tumors to identify bacterial niches and their impact on tumor transcriptomes, highlighting C. difficile's significant influence despite low abundance.

The paper shows that intermicrovillar adhesion complexes limit bacterial attachment to the small intestine brush border, with SFB remodeling actin to anchor to epithelial junctions.

The paper shows that apical clathrin-coated pits regulate microvillar growth by controlling their location, timing, and size during epithelial differentiation.