Author

Alexander Friedman

Duke UniversityPrimary ORCID profile (0009-0006-0882-5324 · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Alexander FriedmaniD4 papers · The University of Texas at El Paso

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Çağla EroğluiD· 2 shared Francesco Paolo Ulloa SeverinoiD· 2 shared Henry H. YiniD· 2 shared Sarah A. JohnsoniD· 2 shared Bryan Lu· 1 shared Chaichontat SriworaratiD· 1 shared Il Hwan KimiD· 1 shared Jiwon KimiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

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10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Çağla EroğluORCID

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2 papers

Recent·Most cited

Elucidating an anterior cingulate circuit for self-initiated actions and rescue of Parkinsonian akinesia

Francesco Paolo Ulloa Severino, Bryan Lu, Jiwon Kim, Alexander Friedman, Marina A. Roshchina, Sarah A. Johnson, Konstantin I. Bakhurin, Çağla Eroğlu, Henry H. Yin

This study identifies a cortical circuit involving ACC-D1+ neurons critical for initiating goal-directed movements and shows its therapeutic potential in Parkinsonian akinesia.

bioRxiv · Dec 3, 2025 · PreprintNeuroscience

Training-Induced Circuit-Specific Excitatory Synaptogenesis is Required for Effort Control

Francesco Paolo Ulloa Severino, Oluwadamilola O. Lawal, Kristina Sakers, Shiyi Wang, Namsoo Kim, Alexander Friedman, Sarah A. Johnson, Chaichontat Sriworarat, Ryan N. Hughes, Scott H. Soderling, Il Hwan Kim, Henry H. Yin, Çağla Eroğlu

This study shows that training-induced excitatory synaptogenesis in the ACC->DMS circuit is required for effort control, not learning, and is mediated by the 2{delta}-1 protein.

bioRxiv · Apr 20, 2021 · PreprintNeuroscience