Alexander G. J. Skorput

The paper identifies regionally distinct CD8+ resident memory T cells in the human CNS shaped by viral infections using single-cell RNA sequencing and T cell receptor analysis.

This study identifies that circulating and brain-resident memory CD8+ T cells contribute to distinct bystander TRM-like populations in glioblastoma, with brain TRM being a major source in GBM.

This study shows brain-resident memory T cells (TRM) can rapidly remodel the CNS immune landscape through activation of multiple immune cells, and PD-1 inhibits granzyme B but not alarm responses.

This study identifies CD39 expression on functional effector and tissue-resident memory CD8+ T cells, showing its role in memory differentiation and function, distinct from its role in T cell exhaustion.

This study compares the transduction efficiency of AAV9 and AAV2retro vectors in the somatosensory system using reporter expression in transgenic mice.

This study shows that bumetanide, an NKCC1 antagonist, prevents ethanol-induced interneuronopathy and behavioral deficits in a FASD model.