The MuvB Complex Binds and Stabilizes Nucleosomes Downstream of the Transcription Start Site of Cell-Cycle Dependent Genes
Anushweta Asthana, Parameshwaran Ramanan, Alexander Hirschi, Keelan Z. Guiley, Tilini U. Wijeratne, Robert I. Shelansky, Michael J. Doody, Haritha Narasimhan, Hinrich Boeger, Sarvind Mani Tripathi, Gerd A. Müller, Seth M. Rubin
This study determines the structure of the MuvB complex and shows it binds and stabilizes nucleosomes downstream of the transcription start site to repress gene expression.
Nature Communications · Jan 26, 2022Peer-reviewedMolecular Biology