Author

Gerd A. Müller

University of California, Santa CruzORCID 0000-0002-4967-2487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Seth M. RubiniD· 3 shared Tilini U. WijeratneiD· 3 shared Abolfazl Zargari· 1 shared Alexander Hirschi· 1 shared Alison K. BarrettiD· 1 shared Andreas RechtsteineriD· 1 shared Anushweta AsthanaiD· 1 shared Benjamin R. TopacioiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Seth M. RubinORCID

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3 papers

Recent·Most cited

E2F1 induces a G0-G1 reentry transcriptional program without changing chromatin accessibility

Gerrald A. Lodewijk, Benjamin R. Topacio, Seung‐Ho Lee, Sayaka Kozuki, Znala Williams, Clara J. Han, Abolfazl Zargari, Tilini U. Wijeratne, Neda Hajiakhoond Bidoki, Silvart Arabian, Edward Wu, Eric Malekos, Joscha Weiss, Gerd A. Müller, Vanessa D. Jönsson, , S. Ali Shariati

The paper shows E2F1 induces cell-cycle reentry without changing chromatin accessibility by using pre-existing regulatory elements.

bioRxiv · Sep 23, 2025 · PreprintCell Biology

HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes

Alison K. Barrett, Manisha R. Shingare, Andreas Rechtsteiner, Kelsie M. Rodriguez, Quynh Ngoc Le, Tilini U. Wijeratne, Corbin E. Mitchell, Miles W. Membreño, Seth M. Rubin, Gerd A. Müller

This study shows that DREAM and E2F:RB complexes can repress cell-cycle genes without HDAC activity, challenging the canonical role of HDACs in this process.

Nature Communications · May 24, 2024Peer-reviewedMolecular Biology

The MuvB Complex Binds and Stabilizes Nucleosomes Downstream of the Transcription Start Site of Cell-Cycle Dependent Genes

Anushweta Asthana, Parameshwaran Ramanan, Alexander Hirschi, Keelan Z. Guiley, Tilini U. Wijeratne, Robert I. Shelansky, Michael J. Doody, Haritha Narasimhan, Hinrich Boeger, Sarvind Mani Tripathi, Gerd A. Müller, Seth M. Rubin

This study determines the structure of the MuvB complex and shows it binds and stabilizes nucleosomes downstream of the transcription start site to repress gene expression.

Nature Communications · Jan 26, 2022Peer-reviewedMolecular Biology