Author

Alexander J. Lanz

University of Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. GarviniD· 3 shared Joanna R. MorrisiD· 3 shared Alexandra K. Walker· 2 shared Aneika C. LeneyiD· 1 shared Benjamin F CooperiD· 1 shared George E. RonsoniD· 1 shared Hannah L. Mackay· 1 shared Jai S. BhachooiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMolecular Biology

Alexander J. GarvinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SUMO4 promotes SUMO deconjugation required for DNA double-strand break repair.

Alexander J. Garvin, Alexander J. Lanz, George E. Ronson, Matthew J.W. Mackintosh, Katarzyna Starowicz, Alexandra K. Walker, Yara Aghabi, Hannah L. Mackay, Ruth M. Densham, Jai S. Bhachoo, Aneika C. Leney, Joanna R. Morris

This study identifies SUMO4 as a critical regulator of DNA double-strand break repair by promoting SUMO deconjugation through SENP1 and preventing excessive SUMOylation.

Molecular Cell · Mar 1, 2025Peer-reviewedMolecular Biology

SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect SUMO conjugate types.

Alexander J. Garvin, Alexander J. Lanz, Joanna R. Morris

The paper evaluates twenty-four anti-SUMO monoclonal antibodies for their sensitivity, specificity, and ability to detect different SUMO conjugation states across multiple assays.

bioRxiv · Mar 19, 2022 · PreprintMolecular Biology

The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity.

Alexandra K. Walker, Alexander J. Lanz, Mohammed Jamshad, Alexander J. Garvin, Peter J. Wotherspoon, Benjamin F Cooper, Timothy J. Knowles, Joanna R. Morris

This study shows that SAE2 deacetylation during mitosis biases SUMO2 over SUMO1 conjugation, affecting mitotic fidelity through SUMOylation of NuMA.

bioRxiv · Mar 18, 2022 · PreprintMolecular Biology